Biography:

   Pioneering single-molecule super-resolution microscopy and imaging-based spatial multi-omics, his work uncovers synaptic nanocolumns and the structural mechanisms of synaptic transmission and plasticity in hippocampal circuits and disease. He received the Brain & Behavior Research Foundation Young Investigator Award and publishes as corresponding author in Nature, Nature Methods, and Nature Neuroscience. His research is highlighted by Nature, Nature Reviews Neuroscience, and F1000, and incorporated into leading textbooks, including Luo’s Principles of Neurobiology and China’s 101-series “Introduction to Neurobiology.” He holds a BS and PhD in Biophysics from Peking University and trained in neurobiology at the University of Maryland.

Research Interest:

lNanoscale synapse biology with single-molecule super-resolution (e.g., MINFLUX): Decoding nanocolumn architecture, transmission, and plasticity in hippocampal circuits and their roles in neurological disease.

lImaging-based spatial multi-omics at subcellular resolution: Developing automated, end-to-end platforms for centimeter-scale brain mapping, AI-driven analysis, and cross-scale integration from molecular dynamics to circuit function and pathology.

What You Can Expect in the Project:

lGain hands-on experience with cutting-edge single-molecule super-resolution imaging, from sample prep and acquisition to data analysis and interpretation.

lLearn state-of-the-art imaging-based spatial genomics techniques and explore their applications in neurobiology, including mapping gene expression at subcellular resolution in brain tissue.

Desired skill and background:

lPassion for emerging bioimaging technologies

lA strong curiosity to explore the unknown